Celecoxib - Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis is a type of arthritis which is present most common in children. Previously it is called as juvenile rheumatoid arthritis, in order to differentiate between adult arthritis and adult arthritis, the name has been changed recently to juvenile idiopathic arthritis.
The immune system affects the synovium, which leads to secretion of excess synovial fluid leading to swelling, pain and stiffness. It affects all parts of the body. It is an autoimmune disorder where our own immune system itself causes the damages. If proper treatment is not provided it affects the child’s normal growth pattern and development. There are different sub types of juvenile idiopathic arthritis (JIA). The main sub types include systemic arthritis, Oligoarthritis, Polyarthritis, Psoriatic arthritis and Enthesitis related arthritis.
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Morning stiffness, painful stiffened joints , tenderness, limping, fever, rashes, weight loss, irritability and eye redness, pain in eye and blurred vision are some of the symptoms of JIA. There is no exact reason of JIA, but scientist has found out that certain factors either in single or in combination triggers the onset of JIA. Some of the causative factors of JIA are infection, genetics and environmental factors affecting immune system. The prevalence rate is 1 among 1000 children are affected by JIA. Physical examination, X- ray, MRI and complete medical history of the patients are used to diagnose the disease.
The disease is treated by using drugs, exercise, physical and occupational therapy. The main of the treatment is to control the pain, reduce swelling, to increase the joint strength and mobility. Non steroidal anti-inflammatory drugs, corticosteroids, disease- modifying anti- rheumatic drugs and biological modifying agents are some of the drugs used in the treatment of JIA. JIA affects each child differently. Early detection and treat may help to control inflammation and further joint damages and complications.
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